A callus (or callous) is an especially toughened area of skin which has become relatively thick and hard as a response to repeated contact or pressure. In botany, the term is also used to announce a condition of thickened surfaces of leaves or other plant parts. Since repeated contact is required, calluses are most often found on hands or feet. Calluses are generally not harmful, but may sometimes lead to other problems, such as infection. Shoes that fit tightly can often produce calluses on the feet. String instrument players develop calluses where their fingers make contact with the strings, but these calluses are often desirable as they help alleviate the pain from the tension of the strings and make playing easier. Dancers often develop calluses on the soles of their feet from dancing barefoot, which makes performing turns less difficult. Video game players may develop calluses on their thumbs, especially if playing a handheld console with a D-pad such as a PSP. citation needed]