Fluoxetine hydrochloride (Prozac) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.
Fluoxetine is approved for the treatment of depression (including pediatric depression), obsessive-compulsive disorder (in both adult and pediatric populations), bulimia nervosa, panic disorder and premenstrual dysphoric disorder. Other indications include hypochondriasis and body dysmorphic disorder.
Despite the availability of newer agents, it remains extremely popular. Over 21.7 million prescriptions for generic formulations of fluoxetine were filled in the United States in 2006 making it the third most prescribed antidepressant.